Model's Description:
Multiple Mechanisms-of-Action of Corticosteroids 3D Model.
Download Multiple Mechanisms-of-Action of Corticosteroids in various files formats such as Wavefront Object format, Autodesk FBX, DirectX 9.0, Stereo Lithography and HTML5 JSON format.
Corticosteroids exert their physiological effects through multiple mechanisms of action. Clockwise from upper left: 1) They inhibit movement of white blood cells to injured areas, preventing the release of inflammatory cytokines that accompany the immune response. 2) They stabilize biological membranes, including the phospholipid bilayer (by inhibiting phospholipase and arachidonic acid metabolism, thereby preventing the formation of prostaglandins and leukotrienes) and lysosomal membranes (thus preventing the release of histamine, bradykinin, and enzymes). 3) They inhibit phagocytosis and lymphocyte activity. 4) They decrease protein synthesis, inhibiting the activity of fibroblasts, reducing collagen formation, and inhibiting tissue repair 3D Model is ready to download for free, this model contains 52036 polygons.